Research projects

UroCCR's research projects encompass retrospective studies based on existing data, prospective interventional studies, and translational research.

Key stages of an ancillary project

Ongoing

Ongoing

Transcriptomic Analysis of advanced renal cell carcinoma to identify Key genomic signatures predicting clinical response to next-generation anti-VEGFR Therapy and dual Immune Checkpoint inhibition

Project No.

269

Acronym

TAKTIC

Name of the coordinator

Dr Mathieu Larroquette

Project status

Ongoing

Centre

CHU Bordeaux

Keywords

kidney cancer

View details

Project scope

Retrospective Study – Monocentre

Date of publication

01/12/2025

Data controller

Main objective

The objective of our study is to identify predictive signatures of response to IO-IO and to next-generation TKIs in ccRCC, through tumor bulk RNA sequencing of a patient cohort, to support personalized selection of optimal therapeutic combinations.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Caractéristiques et devenir des patients traités par immunothérapie néoadjuvante pour cancer du rein localisé : étude rétrospective multicentrique

Project No.

267

Acronym

NEO-IMMUNO-REN

Name of the coordinator

Dr Fabien Moinard-Butot, Dr Victor Gaillard, Prof. Hervé Lang, Dr Philippe Barthelemy

Project status

Ongoing

Centre

CHU Strasbourg

Keywords

View details

Project scope

Retrospective Study – Multicentre

Date of publication

12/12/2025

Data controller

CHU Strasbourg – CHU Bordeaux

Main objective

Caractéristiques et devenir des patients traités par immunothérapie néoadjuvante pour cancer du rein localisé : étude rétrospective multicentrique

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Survival in the context of renal replacement therapy after energy-based treatment or nephrectomy.

Project No.

262

Acronym

SIREN

Name of the coordinator

Dr Victor GAILLARD
Pr Hervé LANG

Project status

Ongoing

Centre

Strasbourg University Hospital

Keywords

View details

Project scope

Retrospective Study – Multicentre

Date of publication

13/01/2026

Data controller

CHU Strasbourg – CHU Bordeaux

Main objective

Describir la supervivencia global de los pacientes cuyo tratamiento local de un tumor renal se complicó con insuficiencia renal terminal que requirió hemodiálisis.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Corrélation entre paramètres radiomiques CT et IRM des carcinomes rénaux à cellules claires (ccCCR) et leur grade histologique : vers une prédiction non invasive de l’agressivité tumorale.

Project No.

260

Acronym

CLARITY

Name of the coordinator

Marwan HAJOUI
Dr Eva JAMBON

Project status

Ongoing

Centre

Bordeaux University Hospital Centre

Keywords

renal

View details

Project scope

Retrospective Study – Multicenter

Date of publication

06/10/2025

Data controller

Main objective

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Évaluation de l’intégration de données synthétiques dans les essais cliniques randomisés : application à l’étude P-NeLoP

Project No.

259

Acronym

Syn-NeLoP

Name of the coordinator

Prof. Jean-Christophe BERNHARD

Project status

Ongoing

Centre

Bordeaux University Hospital Centre

Keywords

clinical trials

View details

Project scope

Retrospective Study – Multicenter

Date of publication

08/09/2025

Data controller

Main objective

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Évaluation comparative des méthodes d’analyse statistique sur données synthétiques et réelles en IRM multiparamétrique des petites tumeurs rénales

Project No.

255

Acronym

IRM-SYN

Name of the coordinator

Prof. Jean-Christophe BERNHARD

Project status

Ongoing

Centre

Bordeaux University Hospital Centre

Keywords

MRI

View details

Project scope

Retrospective Study – Multicenter

Date of publication

08/09/2025

Data controller

Main objective

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Impact de la prise d’aspirine après chirurgie curative sur le risque de récidive du cancer du rein

Project No.

254

Acronym

AspiCaRe

Name of the coordinator

Prof. Jean-Christophe BERNHARD
Dr Gaëlle MARGUE

Project status

Ongoing

Centre

Bordeaux University Hospital Centre

Keywords

kidney cancer

View details

Project scope

Retrospective Study – Multicenter

Date of publication

07/07/2025

Data controller

Main objective

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Impact de l’âge et du sexe dans l’agressivité des RCC et la réponse aux traitements de 1ere ligne dans les RCC métastatique

Project No.

250

Acronym

AGRESSE-RCC

Name of the coordinator

Gilles Pages/Maeva Duffies

Project status

Ongoing

Centre

IRCAN, CNRS, INSERM – Nice

Keywords

View details

Project scope

Retrospective Study – Multicenter

Date of publication

24/10/2025

Data controller

Main objective

1- Confirm the importance of age in the aggressiveness of RCC (DFS and OS); 2- Determine the importance of sex (female vs male) in the aggressiveness of RCC; 3- Determine the importance of age in the effectiveness of first-line treatments for metastatic disease (PFS and OS); 4- Determine the importance of sex (female vs male) in the efficacy of first-line treatments for metastatic disease (PFS and OS)

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Optimisation du suivi post-néphrectomie dans le CCR localisé : intégration des risques compétitifs de mortalité

Project No.

249

Acronym

SPIN-CCR

Name of the coordinator

Dr Jérémy Mercier, Dr Anne Sophie Bajeot, Dr Thomas Prudhomme

Project status

Ongoing

Centre

CHU Toulouse

Keywords

View details

Project scope

Retrospective Study – Multicenter

Date of publication

07/07/2025

Data controller

Main objective

Determine the duration of oncological follow-up for patients treated with surgery or thermal ablation for localised or locally advanced RCC.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Partial nephrectomy in patients with chronic kidney disease : Impact of surgical approach

Project No.

246

Acronym

PICKS

Name of the coordinator

Dr Olga Katzendorn, Dr Jean-Baptiste Beauval, Dr Benjamin Pradere

Project status

Ongoing

Centre

Clinique La Croix du Sud

Keywords

View details

Project scope

Retrospective Study – Multicenter

Date of publication

07/07/2025

Data controller

Main objective

To assess the impact of surgical strategy (open vs. robotic partial nephrectomy) on short-term and long-term renal function in patients with CKD>2.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

When Anatomy Gets Complicated: 3D-IGRAPN for Tumors in Horseshoe Kidneys — A Multicenter International Experience

Project No.

244

Acronym

Horseshoe-3D-IGRAPN

Name of the coordinator

Dr Federico Rubat-Baleuri
Dr Gaëlle Margue

Project status

Centre

CHU Bordeaux

Keywords

View details

Project scope

Retrospective Study – Monocentre

Date of publication

18/06/2025

Data controller

Main objective

Assess the feasibility of the 3D-IGRAPN technique in horseshoe kidney cancer

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Chirurgie de précision : la technique de Néphrectomie Partielle Robot-Assistée guidée par l’imagerie 3D (3D-IGRAPN) aide à surmonter les défis des tumeurs rénales complexe (score RENAL ≥7)

Project No.

242

Acronym

Complexe-3D-IGRAPN

Name of the coordinator

Dr Federico Rubat-Baleuri
Prof. Jean-Christophe Bernhard

Project status

Ongoing

Centre

CHU Bordeaux

Keywords

View details

Project scope

Retrospective Study – Multicenter

Date of publication

03/03/2025

Data controller

Main objective

Compare the trifecta achievement rate in patients with medium- or high-complexity tumours with or without 3D-IGRAPN.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Néphrectomie totale : existe-il un bénéfice à la voie robot-assistée par rapport à la coelioscopie standard ?

Project No.

241

Acronym

RoVsLap

Name of the coordinator

Dr Nicolas Branger

Project status

Ongoing

Centre

IPC Marseille

Keywords

View details

Project scope

Retrospective Study – Multicentre

Date of publication

07/04/2025

Data controller

Main objective

Assess whether robot-assisted radical nephrectomy is associated with a reduction in postoperative complications compared to the laparoscopic approach.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Récidive après traitement thermo-ablatif : impact du type histologique et prise en charge

Project No.

239

Acronym

ABLAREC

Name of the coordinator

Dr Taha Fayek

Project status

Ongoing

Centre

CHU Reims

Keywords

View details

Project scope

Retrospective Study – Multicenter

Date of publication

07/04/2025

Data controller

Main objective

Study the impact of histological type on recurrence in patients with malignant renal tumours treated with thermal ablation therapy.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Benefits of robot-assisted partial nephrectomy guided by 3D modeling (3D-IGRAPN) in patients with chronic renal failure and/or a single kidney, after propensity score matching.

Project No.

238

Acronym

IRC-3D-IGRAPN

Name of the coordinator

Dr Maxime PATTOU
Pr Jean-Christophe BERNHARD

Project status

Ongoing

Centre

Bordeaux University Hospital

Keywords

View details

Project scope

Retrospective Study – Multicenter

Date of publication

03/03/2025

Data controller

Main objective

Compare the trifecta achievement rate between the two populations with and without matched 3D-IGRAPN.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Analysis of Radiomic Signatures for Predicting Tumor Aggressiveness in Kidney Cancer

Project No.

237

Acronym

RADIOMIC-CCR

Name of the coordinator

Pr Jean-Christophe BERNHARD
Dr Gaëlle MARGUE
Dr Maxime PATTOU

Project status

Ongoing

Centre

Bordeaux University Hospital

Keywords

View details

Project scope

Retrospective Study – Monocentre

Date of publication

09/12/2024

Data controller

Main objective

Évaluer l’association entre la signature radiomique du scanner préopératoire et l’agressivité tumorale.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Sparing versus Radical Nephrectomy for cT2 Renal Cell Carcinoma: A National Matched-Pair Analysis

Project No.

235

Acronym

SpaRT2

Name of the coordinator

Dr Rajaa ET-TOUZANI
Dr Gaëlle MARGUE

Project status

Ongoing

Centre

Dijon University Hospital / Bordeaux University Hospital

Keywords

View details

Project scope

Retrospective Study – Multicenter

Date of publication

06/01/2025

Data controller

Main objective

To evaluate the feasibility and oncological outcomes of NPRA surgery in the management of cT2-classified renal tumors. The primary endpoint is 2-year DFS.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Comparison of the efficacy and safety of cryotherapy versus partial nephrectomy in the management of endophytic or hilar renal lesions.

Project No.

234

Acronym

SACRYPAN

Name of the coordinator

Dr Matthieu GARNIER
Dr Louis SURLEMONT

Project status

Ongoing

Centre

Rouen University Hospital

Keywords

View details

Project scope

Retrospective Study – Multicenter

Date of publication

03/03/2025

Data controller

Main objective

Compare the efficacy and safety of cryotherapy versus robot-assisted partial nephrectomy for endophytic lesions.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Is the complexity of renal tumors after partial nephrectomy predictive of postoperative false aneurysms?

Project No.

232

Acronym

PseudoA-PN

Name of the coordinator

Dr Mathilde BRUMENT
Dr Louis SURLEMONT

Project status

Ongoing

Centre

Rouen University Hospital

Keywords

View details

Project scope

Retrospective Study – Multicenter

Date of publication

03/02/2025

Data controller

Main objective

Determine whether the complexity of renal tumors after partial nephrectomy is a risk factor for postoperative false aneurysm

Resources

Publications

There are no publications yet for ongoing projects.

Contacts

Ongoing

Ongoing

Renal biopsy in localized kidney cancers: what factors are associated with discordance with definitive histology?

Project No.

230

Acronym

BIRD

Name of the coordinator

Dr Stessy KUTCHUKIAN
Pr François AUDENET

Project status

Ongoing

Centre

Poitiers University Hospital / HEGP

Keywords

View details

Project scope

Retrospective Study – Multicenter

Date of publication

02/12/2024

Data controller

Main objective

Identify the clinical and radiological factors associated with a discrepancy between the histology obtained by biopsy and the definitive histology in localized renal tumors, regardless of histological type.

Resources

Publications

There are no publications yet for ongoing projects.

Contacts